A 78-year-old male who for 2 years had been treated for liver cirrhosis developed bilateral leg edema, at our hospital. After admission, he was diagnosed as having gastric cancer with protein-losing gastroenteropathy based on endoscopy, RI scan, and gastric juice protein density. The patient's leg edema and hypoprotenemia were not caused by the cirrhosis but by the gastric cancer with a protein-losing gastroenteropathy. The patient's serum protein and albumin levels improved immediately post distal gastrectomy ; the patient no longer had leg edema.