With the development of information technology, technology mining technology can help users to find the needed information accurately and efficiently. In this paper, the author makes factors analysis of professional growth of innovative talents based on data mining technology. Knowledge innovation is the starting point of scientific and technological innovation, and the development of innovative talents is the most important and the scarcest resource for enterprises. By analyzing the professional growth of innovative talents, we construct the evaluation index system of innovative talents. The conclusion proves that the balance between supply and demand of enterprise and personal professional growth is the important factor to promote organizational technology progress and the career development of employees.