This study aimed to introduce International Maritime Organization (IMO)’s standards on the ship’s fumigation for national legislation. Careless use of pesticides on ships can threaten the health and life of employees. Since ship fumigation is mainly conducted in ports in our nation, the study intends to explore the legal status of ship fumigation and to prepare measures by improving domestic laws. To this end, the current domestic laws related to the implementation of ship fumigation and disinfection were investigated, and the regulations of the IMO international convention, guidelines, and laws of foreign countries were also reviewed. As a result, it was possible to identify the standards to be accepted in domestic law. Moreover, the relevant regulations needed to include management methods from the perspective of seafarers. To introduce the IMO guidelines related to fumigation, specific standards to be accepted in the domestic laws were derived by comparing and analyzing the contents of domestic laws and the relevant IMO regulations about ships’ fumigation. Among the pesticides used during fumigation of ships, information on dangerous methyl bromide and phosphine, information on several pesticides available according to the loading condition of the ship's cargo hold, and checklists to be used by the master and fumigator-in-charge should be provided. Finally, for the safe use of pesticides in ships, essential contents to be reflected in the minister’s notice of ship’s fumigation under the Ship Safety Act were proposed. This study can contribute to the safe use of pesticides during onboard fumigation and to strengthening the safety management of ships by government authorities including the Korean coast guard.