This study aimed to develop an Interprofessinal Education(IPE) program for third-year healthcare students to provide patient safety-oriented services and demonstrate professionalism, and to determine the effects of applying the program for five days on patient safety knowledge and patient safety performance confidence. Key topics included understanding job roles by profession, training in patient risk prediction, scenario-based patient experience, and strategies for identifying improvement. As a result of the study, after the application of the IPE program, the patient safety knowledge decreased statistically significantly from 39 points to 37 points(p=.007). The patient safety performance confidence increased statistically significantly from 6.71 pints to 7.50 points(p<.001). In addition, students who experienced clinical practice had higher patient safety knowledge after applying the IPE program, but there was no difference in patient safety performance. Repeated studies are recommended to prove the effectiveness of the IPE program, and specific measures should be taken to expand and continuously manage the IPE program.