Since many scientific and technological achievements are difficult to be transformed and cannot be achieved manually, this paper carries out a scientific and technological achievements transformation system from the perspective of data mining technology, aiming to convert achievements into data by relying on data mining technology. Firstly, the basic concepts and characteristics of the system are introduced. Secondly, GMDH algorithm is adopted to design the system. With the support of algorithm, the system can realize the transformation of scientific research and technology achievements and has practical value.