Fabrication and Characterization of a Multiwall Carbon Nanotube Needle Biosensor
- Resource Type
- Conference
- Authors
- YeoHeung Yun; Bange, A.; Shanov, V.N.; Heineman, W.R.; Halsall, H.B.; Zhongyun Dong; Jazieh, A.; Yi Tu; Wong, D.; Pixley, S.; Behbehani, M.; Schulz, M.J.
- Source
- 2006 Sixth IEEE Conference on Nanotechnology Nanotechnology, 2006. IEEE-NANO 2006. Sixth IEEE Conference on. 1:280-283 2006
- Subject
- Components, Circuits, Devices and Systems
Fabrication
Carbon nanotubes
Needles
Biosensors
Sensor arrays
Steady-state
Sugar
Costs
Molecular biophysics
Sensor phenomena and characterization
Multiwall Carbon Nanotube
Biosensor
- Language
- ISSN
- 1944-9399
A nanotube electronic needle biosensor was developed to provide fast, low cost, accurate detection of biomolecules. The sensor was formed by synthesizing highly aligned multi-wall carbon nanotube arrays. Nanotube bundles from the array were welded onto the tips of tungsten needles using a microscope. The needles were then encased in glass and a polymer coating. Cyclic voltammetry (CV) for the respective reduction of 6 mM K 3 Fe(CN) 6 in a 1.0 M KNO 3 was performed to examine the redox behavior of the nanotube needle. The CV results showed a steady-state response attributable to radial diffusion with a high steady-state current density. An amperometric sensor was then developed for glucose detection by physical attachment of glucose oxidase on the nanotube needle. A label-free immunosensor based on electrochemical impedance spectroscopy was also formed. The nanotube needle amperometric have good sensitivity with a low detection limit, and the possibility exists to keep decreasing the size of the needle to increase the sensitivity.