This paper focuses on studying the potential of CO2 emission reduction by putting electric vehicles into operation to replace traditional fuel-use vehicles and to contribute to achieving sustainable development goals in Phu Quoc, Kien Giang, Vietnam. The paper employed numerous planning data of Phu Quoc for the period of 2020 – 2030 related to the population increase, forecasted income per capita, computed growth of vehicles by fossil fuels. Also, the paper has launched a technology diffusion model and different approaches on electric vehicle market, refer to policy frameworks of many countries around the world to promote electric vehicles development. On that basis, the author proposes numerous electric vehicle scenarios to penetrate the market and determine the potential of CO2 emission reduction by 2030. At the same time, the author releases suggestions on policy frameworks and recommendations so that the research results could be soon implemented in practice. With the forecast until 2030, the emission resulted by fossil fuel vehicles is about 79,901 tons. Through the policy framework proposals for the government in the development of electric vehicles, it is forecasted that CO2 emission reductions will be from 13,859 to 16,489 tons of C02/year, corresponding to a reduction of 17-20% for scenarios. Research results show that if the proposed policy frameworks are implemented soon and the introduction of electric vehicles to replace traditional fuel vehicles in Phu Quoc is necessary and feasible not only in terms of ability reduce CO2 emissions, but also contribute to local development to become a regional and international green tourism destination.