Near infrared spectroscopic evaluation of water in hyaline cartilage
- Resource Type
- Conference
- Authors
- Padalkar, M; Spencer, R; Pleshko, N
- Source
- 2012 38th Annual Northeast Bioengineering Conference (NEBEC) Bioengineering Conference (NEBEC), 2012 38th Annual Northeast. :370-371 Mar, 2012
- Subject
- Bioengineering
Communication, Networking and Broadcast Technologies
Components, Circuits, Devices and Systems
Computing and Processing
Signal Processing and Analysis
Robotics and Control Systems
Cartilage
Spectroscopy
Osteoarthritis
Magnetic resonance imaging
- Language
- ISSN
- 2160-6986
2160-7028
2160-7001
Articular cartilage is avascular and has limited capacity for repair. In diseased conditions such as osteoarthritis, there is an increase in water content from the average normal of 60–85% to greater than 90%. As cartilage has very little capability for self-repair, methods of early detection of degeneration are required, and assessment of water could prove to be a useful diagnostic method. Non-destructivenear infrared spectroscopyis extremely sensitive to the chemical composition and molecular structure of tissues and could prove to be a useful method for early diagnosis of cartilage degeneration. The hypothesis that NIR spectra can be used to assess water content in cartilage was investigated in the current study.