Robust blood glucose regulation for Type II Diabetes Mellitus patients
- Resource Type
- Conference
- Authors
- Herrera, Karla G.; Ruiz-Velazquez, E.; Garcia-Rodriguez, J.
- Source
- 2017 IEEE International Autumn Meeting on Power, Electronics and Computing (ROPEC) Power, Electronics and Computing (ROPEC), 2017 IEEE International Autumn Meeting on. :1-6 Nov, 2017
- Subject
- Bioengineering
Communication, Networking and Broadcast Technologies
Components, Circuits, Devices and Systems
Computing and Processing
Engineering Profession
General Topics for Engineers
Power, Energy and Industry Applications
Robotics and Control Systems
Signal Processing and Analysis
Sugar
Insulin
Blood
Diabetes
Mathematical model
Transfer functions
Robustness
- Language
- ISSN
- 2573-0770
This paper presents a H ∞ robust controller to glycemic control in Type 2 Diabetes Mellitus (T2DM) patients. The proposed control action calculates the insulin delivery rate in order to prevent hypoglycemic and hyperglycemic levels in patients. A nonlinear compartmental model that represents the glucose regulation behavior for T2DM subjects was linearized around a nominal healthy subject conditions, and then reduced for synthesis design. Unstructured uncertainties were considered in model based on sensitivity analysis and a 10th order robust controller was derived with a γ = 0.9921. The proposed scheme uses as a reference glucose values of a healthy patient. The applicability of the proposed control scheme is shown via simulations for a scenario of three daily intakes.