Multiple-input, multiple-output (MIMO) technology has become a very promising wireless communication method. It presents a possible solution for solving traffic capacity constraints in high-speed wireless broadband network access. MIMO systems enhance the efficiency and performance of wireless communication systems through the use of multiple antennas at both the transmitting and receiving ends. This paper provides a comprehensive analysis of multiple-input multiple-output (MIMO) antenna design methodologies for fifth-generation (5G) and beyond wireless communication systems. This paper provides a thorough analysis of the performance characteristics of Multiple-Input Multiple-Output (MIMO) systems, focusing on isolation, efficiency, gain, antenna type, and Envelope Correlation Coefficient (ECC). In addition, the benefits of MIMO technology over traditional Single-Input Single-Output (SISO) systems are discussed.