Computational Sensing with a Multiplexed Vertical Flow Assay for High-Sensitivity C-Reactive Protein Quantification
- Resource Type
- Conference
- Authors
- Ballard, Zachary S.; Joung, Hyou-Arm; Goncharov, Artem; Liang, Jesse; Nugroho, Karina; Di Carlo, Dino; Garner, Omai B.; Ozcan, Aydogan
- Source
- 2020 Conference on Lasers and Electro-Optics (CLEO) Lasers and Electro-Optics (CLEO), 2020 Conference on. :1-2 May, 2020
- Subject
- Photonics and Electrooptics
Sensors
Multiplexing
Proteins
Testing
Immune system
Biomembranes
Cardiovascular diseases
- Language
We demonstrate computational sensing with a multiplexed paper-based point-of-care assay for high sensitivity C-Reactive protein testing (hsCRP). Using blindly-tested human serum samples, we achieved an R 2 value of 0.95 and an average coefficient-of-variation of 11.2%.