With the rapid development of high technology and economy, our country has entered a new era of artificial intelligence in the 21st century. Home appliances of artificial intelligence, auxiliary software of artificial intelligence, learning tools of artificial intelligence, etc., have gradually become an inseparable part of national life, so the flourishing development of information technology and network makes people’s life more convenient and efficient, but at the same time, because we are in the new era of artificial intelligence, these applications in different fields not only help to improve the efficiency of work in various fields, but also give The computer network information security protection technology brings challenges, so information technology and network also has two sides, which computer network information security problems to the country and people bring certain impact and trouble, so this paper discusses and discusses the computer network information security problems in the era of artificial intelligence, and puts forward the corresponding protection countermeasures.