Based on the theory of software engineering, this paper designs a university research project management system based on cloud platform. The system includes project application and review module, project opening management module, project progress management module, project completion management module and project research results display module, which realizes the distributed submission of project declaration, opening report, progress report and conclusion report, and network review. The system has the characteristics of electronic materials, uninterrupted service, office network, automatic results, and feedback zero distance. It effectively solves the problem of declaration review and process management of university research projects, improves project management efficiency, and saves the working hours of project management personnel, review experts and teachers, promotes the university research results and realizes the informationization of university research project management.