This paper presents a general control method for suppressing leakage current. Without the addition of passive devices and switching tubes, the amplitude and effective value of leakage current can be reduced by direct control of common mode current, so that it can meet the relevant standards. The method is based on the traditional single-phase voltage bridge inverter to verify the effect of common-mode control on its leakage current suppression. The working principle, control method and modulation strategy are described in detail. On this basis, the simulation and experiment of open-loop and grid-connected control of full-bridge inverter are completed. The results are good and in agreement with the theoretical analysis.