MRI Contrast Enhancement of Magnetization Prepared Steady State Sequence: An Optimal Control Framework
- Resource Type
- Conference
- Authors
- Vernier, Benoit; Van Reeth, Eric; Pilleul, Frank; Beuf, Oliver; Ratiney, Helene
- Source
- 2021 IEEE 18th International Symposium on Biomedical Imaging (ISBI) Biomedical Imaging (ISBI), 2021 IEEE 18th International Symposium on. :1709-1713 Apr, 2021
- Subject
- Bioengineering
Computing and Processing
Photonics and Electrooptics
Signal Processing and Analysis
In vivo
Image segmentation
Magnetization
Magnetic resonance imaging
Pipelines
Optimal control
Steady-state
GRAPE
Optimal Control
MP-RAGE
- Language
- ISSN
- 1945-8452
The present work investigates the possibilities of enhancing MRI contrast between two target tissues in a three-dimensional Magnetization-Prepared Rapid Gradient-Echo (MP-RAGE) based on relaxation time’s differences. The benefit lies in the adaptation of the GRAPE algorithm to the optimization of a magnetization preparation in a cyclic sequence without full recovery between each cycle. This numerical approach allows optimizing a magnetization preparation of an arbitrary number of radio frequency pulses to enhance contrast, taking in account the establishment of a steady state in the longitudinal component of the magnetization. In vivo validation on rat brain is performed at 11. 7T and shows the benefit of an optimized T 2 Prep-IR compared to a simple inversion to enhance contrast between white and gray matter.