Introduction: Epilepsy is the commonest childhood neurological disorder mostly affecting children in the first decade of life. Globally, school teachers have many false beliefs and misinformation about epilepsy. The knowledge and attitude of teachers towards students with epilepsy have a huge impact on their future life. Aim: To evaluate the knowledge, attitude and self-efficacy of school teachers towards students with epilepsy. Materials and Methods: A cross-sectional study was conducted from 20 August 2022 to 31 October 2022 at BPS GMC for women, Khanpur Kalan, Sonepat, Haryana, India, using self-administered questionnaire including randomly selected 427 school teachers from 15 schools of Haryana (India). The questionnaire included the scale of Attitude Towards Persons with Epilepsy (ATPE), a summated rating scale for measuring knowledge and attitude. Several additional knowledge and attitude items were also evaluated. Effect of socio-demographic characteristics of participants were also evaluated as a predictor of knowledge and attitude. Data was collected and statistics were applied using Statistical Package for the Social Sciences (SPSS) software and p-value