Association between preoperative serum albumin and prognosis in patients with adrenocortical carcinoma after primary resection: a retrospective study
- Resource Type
- article
- Authors
- Fuxun Zhang; Zhihong Liu; Jiayu Liang; Shengzhuo Liu; Kan Wu; Fan Zhang; Chuan Zhou; Yiping Lu; Yuchun Zhu; Xianding Wang
- Source
- BMC Cancer, Vol 21, Iss 1, Pp 1-9 (2021)
- Subject
- Adrenocortical carcinoma
Prognosis
Resection
Albumin
Nutrition
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
- Language
- English
- ISSN
- 1471-2407
Abstract Background Adrenocortical carcinoma (ACC) is a rare and aggressive malignancy with a poor prognosis. Given the limited treatment options, prognostic assessment of ACC is increasingly crucial. In this study, we aim to assess the correlation between preoperative serum albumin and prognosis in patients with ACC after primary resection. Methods We retrospectively collected and reviewed medical information about 71 ACC patients who underwent primary resection. Survival analysis was performed by Kaplan–Meier analysis with log-rank test or Breslow test. Receiver operating characteristic (ROC) curve and Jordan index was generated to explore optimal cut-off value of albumin. Univariate and multivariate analysis was conducted using Cox’s hazards model. Statistical significance was defined as P