Left ventricular function and survival in ischemic cardiomyopathy: Implications for surgical ventricular restorationCentral MessagePerspective
- Resource Type
- article
- Authors
- Srilakshmi M. Adhyapak, DNB; V. Rao Parachuri, FRCS(CTh); Tinku Thomas, PhD; Kiron Varghese, MD, DM
- Source
- JTCVS Open, Vol 7, Iss , Pp 211-218 (2021)
- Subject
- left ventricle
relative wall thickness
surgical ventricular restoration
heart failure
Diseases of the circulatory (Cardiovascular) system
RC666-701
Surgery
RD1-811
- Language
- English
- ISSN
- 2666-2736
Objectives: This pilot study evaluates the association of relative wall thickness (RWT) on survival in patients with ischemic cardiomyopathy (ICM). We hypothesized that patients with preserved RWT may be better candidates for surgical ventricular restoration than those with thinner RWT. Methods: Echocardiography was performed in 165 consecutive patients (aged 58.2 ± 14.7 years) divided into 2 groups based on RWT values. Group 1 had patients with preserved RWT and group 2 had patients with reduced RWT. Results: There were 120 (72.7%) patients with hypertension and 112 (67.8%) patients had diabetes mellitus. The patients with preserved RWT (group 1) had significantly more hypertension and diabetes. The patients with decreased RWT (group 2) were in a higher New York Heart Association functional class and had significantly greater incidence of anterior wall myocardial infarction. The entire cohort was followed over 24 months (group 1: n = 117 and group 2: n = 48). The overall all-cause mortality in group 1 (preserved RWT) was 7 (5.9%) and in group 2 (reduced RWT) was 35 (72.9%) (P