Introduction and purpose: The quality of life of the elderly is endangered by their special needs. The present study aimed to investigate the relationship between social support and health-related quality of life among the elderly in Abadan. Methods: This study was conducted based on a descriptive cross-sectional analytical design. The study sample included 138 elderly people in Abadan. Data collection instruments were the SF36 standard quality of life questionnaire and social support questionnaire. Data were analyzed in SPSS software (version 21) using descriptive statistics, independent t-test, Pearson correlation, and regression at a significance level of 0.05. Results: The results demonstrated that the quality of life of men (91.29±6.2) was higher than women (46.47±22.58), and the difference was significant (P