Image-Guided Treatment of Primary Liver Cancer in Mice Leads to Vascular Disruption and Increased Drug Penetration
- Resource Type
- article
- Authors
- Sara B. Keller; Dingjie Suo; Yak-Nam Wang; Heidi Kenerson; Raymond S. Yeung; Michalakis A. Averkiou
- Source
- Frontiers in Pharmacology, Vol 11 (2020)
- Subject
- ultrasound
drug delivery
vascular disruption
microbubbles
hepatocellular carcinoma
doxorubicin
Therapeutics. Pharmacology
RM1-950
- Language
- English
- ISSN
- 1663-9812
Despite advances in interventional procedures and chemotherapeutic drug development, hepatocellular carcinoma (HCC) is still the fourth leading cause of cancer-related deaths worldwide with a