Elevated NT-proBNP levels are associated with CTP ischemic volume and 90-day functional outcomes in acute ischemic stroke: a retrospective cohort study
- Resource Type
- article
- Authors
- Xiaozhu Shen; Juan Liao; Yi Jiang; Yiwen Xu; Mengqian Liu; Xianxian Zhang; Nan Dong; Liqiang Yu; Qingmei Chen; Qi Fang
- Source
- BMC Cardiovascular Disorders, Vol 22, Iss 1, Pp 1-10 (2022)
- Subject
- Acute ischemic stroke
N-terminal pro-B-type natriuretic
Outcomes
CTP perfusion
Treatment decisions
Diseases of the circulatory (Cardiovascular) system
RC666-701
- Language
- English
- ISSN
- 1471-2261
Abstract Objective To investigate the impact of N-terminal pro-B-type natriuretic peptide (NT-proBNP) on CTP infarct core volume and poor 90-day functional outcomes in acute ischemic stroke (AIS). Methods A total of 403 hospitalized patients with AIS in the Stroke Center of the First Hospital Affiliated to Soochow University were enrolled from March 2018 to January 2021. The association between NT-proBNP and clinical outcomes in acute ischemic patients was assessed by logistic regression and adjusted for confounding factors. Also, subgroup analyses were conducted based on treatment decisions. Results NT-proBNP was positively correlated with CTP ischemic volume (p