Ribonucleoprotein Complexes That Control Circadian Clocks
- Resource Type
- article
- Authors
- Xianyun Chen; Jinhu Guo; Xiaodi Liang; Dongni Wang
- Source
- International Journal of Molecular Sciences, Vol 14, Iss 5, Pp 9018-9036 (2013)
- Subject
- ribonucleoprotein
circadian clock
transcription
translation
post-transcription
Biology (General)
QH301-705.5
Chemistry
QD1-999
- Language
- English
- ISSN
- 1422-0067
Circadian clocks are internal molecular time-keeping mechanisms that enable organisms to adjust their physiology and behavior to the daily surroundings. Misalignment of circadian clocks leads to both physiological and health impairment. Post-transcriptional regulation and translational regulation of circadian clocks have been extensively investigated. In addition, accumulating evidence has shed new light on the involvement of ribonucleoprotein complexes (RNPs) in the post-transcriptional regulation of circadian clocks. Numerous RNA-binding proteins (RBPs) and RNPs have been implicated in the post-transcriptional modification of circadian clock proteins in different model organisms. Herein, we summarize the advances in the current knowledge on the role of RNP complexes in circadian clock regulation.