Anti-N antibody reacting at 37°C: An unusual occurrence interfering with routine testing: Two interesting cases
- Resource Type
- article
- Authors
- Vijay Kumawat; Ashish Jain; Neelam Marwaha; Ratti Ram Sharma
- Source
- Asian Journal of Transfusion Science, Vol 9, Iss 1, Pp 92-93 (2015)
- Subject
- Anti-N antibody
naturally occurring anti-N
warm reacting antibody
Diseases of the blood and blood-forming organs
RC633-647.5
- Language
- English
- ISSN
- 0973-6247
1998-3565
Most anti-N antibodies are naturally occurring, IgM antibodies, and not active above 25°C and are not clinically significant but IgG anti- N has also been described. Immune anti-N resulting from multiple transfusions does occur & has been implicated as the cause of hemolytic transfusion reactions and mild hemolytic disease of fetus and newborn. Anti- N reacting at room temperature can be a cause for ABO blood group discrepancy