Impacts of Antihypertensive Drugs on Coronary Collateral Development
- Resource Type
- article
- Authors
- Uğur KÜÇÜK
- Source
- Ahi Evran Medical Journal, Vol 6, Iss 2, Pp 137-142 (2022)
- Subject
- ace inhibitors
coronary artery disease
coronary collateral circulation
Medicine
- Language
- English
Turkish
- ISSN
- 2619-9203
Purpose: Increase in the number of coronary imaging has caused us to encounter patients with chronic total occlusion (CTO) more often in daily practice. Although clinical trials have demonstrated the importance of collateral circulation, which has significant functions in ischemic myocardial cells, factors affecting the development of collateral circulation remain unclear. Our study aimed to investigate the impact of antihypertensive drugs on collateral development. Materials and Methods: Our retrospective cohort study included 107 patients who were detected to CTO as a result of coronary angiography (CAG) and had been regularly taking the antihypertensive drug for more than six months. The patients were divided into two groups according to the Rentrop classification. Results: Statistically well-developed collaterals were observed in patients using angiotensin-converting enzyme (ACE) inhibitors for more than six months (p