There are high mountains and steep roads in Guizhou Province. Affected by the relatively closed environment, high humidity and other factors, the skid resistance and durability of the highway in tunnels were obviously reduced, which affects the normal operation of the asphalt pavement. Based on the pavement maintenance project of the highway in the Yilaga Tunnel in Guizhou Province, a new kind of epoxy surface treatment maintenance technology for asphalt pavement has been introduced in this paper. Through the comparative analysis of friction coefficient, structural depth and other anti-sliding performance before and after construction, the results has shown that the technology can effectively solve the early diseases and significantly improve the anti-sliding performance of the pavement, and assist to reduce the occurrence of traffic accidents.