Salvianolic acid B from Salvia miltiorrhiza bunge: A potential antitumor agent
- Resource Type
- article
- Authors
- Sha-Sha Guo; Zhen-Guo Wang
- Source
- Frontiers in Pharmacology, Vol 13 (2022)
- Subject
- TCM
traditional Chinese medicine
salvianolic acid B
anticancer activity
apoptosis
mechanism
Therapeutics. Pharmacology
RM1-950
- Language
- English
- ISSN
- 1663-9812
Salvia miltiorrhiza Bunge (Lamiaceae) is a perennial herb widely found in China since ancient times with a high economic and medicinal value. Salvianolic acid B (Sal-B) is an important natural product derived from Salvia miltiorrhiza and this review summarizes the anticancer activity of Sal-B. Sal-B inhibits tumor growth and metastasis by targeting multiple cell signaling pathways. This review aims to review experimental studies to describe the possible anticancer mechanisms of Sal-B and confirm its potential as a therapeutic drug.