Causes of Elevated Levels of Serum CA 19.9 in Patients without Prior Diagnosis of Malignant Disease
- Resource Type
- article
- Authors
- Selcuk Şeber; Savaş Güzel; Ahsen Yılmaz; Sonat Pınar Kara; Tarkan Yetisyigit
- Source
- Southern Clinics of Istanbul Eurasia, Vol 30, Iss 3, Pp 198-203 (2019)
- Subject
- ca 19-9
inflammation
malignancy.
Medicine
- Language
- English
- ISSN
- 2587-0998
INTRODUCTION[|]Serum CA 19.9 is commonly used as a tumor marker for diagnosis and follow-up of gastrointestinal malignancies. However, elevated levels can be found in various clinical conditions.[¤]METHODS[|]A total of 285 patients whose serum CA 19.9 level was ordered from various outpatient clinics other than oncology in a tertiary hospital setting and who had elevated CA 19.9 (>34 U/mL) levels were included in the study group. Statistical analysis of marker levels in relation to diagnosis of patients was performed.[¤]RESULTS[|]Overall, 226 patients with benign disorders and 59 patients with malignant disease had elevated CA 19-9 levels. One hundred ten (39%) patients with increased CA 19-9 levels did not have any significant clinical condition associated with high CA 19-9 values. Median CA 19-9 levels were significantly higher in patients with malignancies than in patients with benign disorders (67.3 vs. 47.9; p