Prevention and treatment of cancers by tumor antigen-expressing Staphylococcus epidermidis
- Resource Type
- article
- Authors
- Oliver Kepp; Laurence Zitvogel; Guido Kroemer
- Source
- OncoImmunology, Vol 12, Iss 1 (2023)
- Subject
- Immunotherapy
Microbiome
Immunity
Immunologic diseases. Allergy
RC581-607
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
- Language
- English
- ISSN
- 2162402X
2162-402X
ABSTRACTIn a recent paper in Science, Chen et al. reported the genetic engineering of S. epidermidis expressing tumor cross-reactive antigens that trigger T cell responses and exhibit anticancer effects after topical administration. Here we discuss direct local effects and indirect systemic effects of exposure to engineered S. epidermidis strains.