Rheumatoid Arthritis Flare-ups Following Immunization with Sinopharm Inactivated Virus-based COVID-19 Vaccine
- Resource Type
- article
- Authors
- Parisa Delkash; Amir Azimi; Niloufar Taherpour; Alireza Rajaei; Faraneh Farsad; Saeid Haji Aghajani
- Source
- طب اورژانس ایران, Vol 10, Iss 1 (2023)
- Subject
- Rheumatoid arthritis
COVID-19
Sinopharm
Flare-ups
Medical emergencies. Critical care. Intensive care. First aid
RC86-88.9
- Language
- English
Persian
- ISSN
- 2383-3645
Introduction: This study aimed to investigate the incidence of rheumatoid arthritis (RA) flare-ups following immunization with the Sinopharm COVID-19 inactivated virus-based vaccine. Methods: We conducted a retrospective observational study at the Rheumatology Clinic of Imam Hossein Hospital, incorporating 200 RA patients in remission undergoing non-biologic Disease-Modifying Antirheumatic Drugs (DMARDs) treatments. A rheumatologist confirmed a flare-up based on patients complain of arthralgia and joint stiffness and complete examination of joints over a three-month period following vaccination. Results: Twelve percent of all included patients experienced symptom recurrence. The average age of patients with flare-ups was significantly higher, but no gender-based differences were observed (p