Evidence of pulmonary arterial hypertension in two patients with common variable immunodeficiency
- Resource Type
- article
- Authors
- Jessica Huston; Joyce Johnson; Anna Hemnes; Meredith Pugh
- Source
- Pulmonary Circulation, Vol 10 (2020)
- Subject
- Diseases of the circulatory (Cardiovascular) system
RC666-701
Diseases of the respiratory system
RC705-779
- Language
- English
- ISSN
- 2045-8940
20458940
Common variable immunodeficiency is a chronic illness plagued with recurrent infections and the potential to develop autoimmune disease. These patients may manifest a spectrum of complications ranging from hematologic malignancy to chronic parenchymal lung disease. Regular immunoglobulin replacement therapy improves immunologic debility but does not mitigate other features of this disease. Here, we discuss a complication of common variable immunodeficiency not previously characterized in the literature. We present two cases of advanced pulmonary vascular disease associated with common variable immunodeficiency treated with pulmonary vasodilators.