Emergency management of a 13-year-old patient with primary mediastinal B cell lymphoma: Extracorporeal membrane oxygenation and superior vena cava stent prior to chemotherapy
- Resource Type
- article
- Authors
- Salvador R. Maffei; Gary Stapleton; Katherine Doane; James Thomas; M Hossein Tcharmtchi; Julienne Brackett; Saleh Bhar
- Source
- Pediatric Hematology Oncology Journal, Vol 9, Iss 3, Pp 129-132 (2024)
- Subject
- Extracorporeal membrane oxygenation
Mediastinal mass
Superior vena cava syndrome
Interventional cardiology
Pediatrics
RJ1-570
- Language
- English
- ISSN
- 2468-1245
Background: Primary mediastinal B cell lymphoma (PMBCL) is a rare type of non-Hodgkin's lymphoma, and prompt diagnosis and initiation of chemotherapy are necessary to limit compression of cardiovascular structures. Case report: A 13-year-old patient was diagnosed with PMBCL, resulting in acute hypoxemic respiratory failure and cardiogenic shock with clinical pericardial tamponade. Chemotherapy was initiated after veno-arterial extracorporeal membrane oxygenation and subsequent endovascular stenting of the superior vena cava (SVC) to optimize cardiac output due to malignant SVC syndrome. Conclusion: We discuss the challenges of diagnosis and emergency management of pediatric patients with PMBCL and review the existing relevant literature for SVC syndrome secondary to PMBCL.