Snezana Tomasevic-Todorovic,1 Atina Vazic,2 Abukari Issaka,3 Fahad Hanna4 1Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia; 2Higher School, College of Professional Studies in Education of Teachers, Kikinda, Serbia; 3Department of Climate and Agriculture, School of Science and Health, Western Sydney University, Sydney, NSW, Australia; 4Department of Public Health, College of Health Sciences, Qatar University, Doha, Qatar Background: Both osteoporosis and osteopenia remain worldwide public health concerns. They both lead to bone fractures, which can lead to disability and burden on those who are afflicted.Objectives: To assess and compare fracture risk between these two groups of patients.Patients and methods: Our cross-sectional study included 82 patients (46 with osteoporosis and 36 with osteopenia) with an average age of 63±9.33 years, who received treatment at the Clinic for Medical Rehabilitation, Clinical Center of Vojvodina in Novi Sad, Serbia. The assessment of the fracture risk was executed by applying the Fracture Assessment Risk (FRAX) index (an algorithm developed by the World Health Organization) based on clinical fracture risks or combination of clinical fracture risks and bone mineral density.Results: Patients with osteoporosis had significantly higher risk of major fracture compared to patients with osteopenia (p