Synthesis of New Riminophenazines with Pyrimidine and Pyrazine Substitution at the 2-N Position
- Resource Type
- article
- Authors
- Haihong Huang; Dali Yin; Xiaojian Wang; Chun Li; Hao Zhang; Gang Zhang
- Source
- Molecules, Vol 16, Iss 8, Pp 6985-6991 (2011)
- Subject
- riminophenazine
N-arylation
palladium catalyst
Organic chemistry
QD241-441
- Language
- English
- ISSN
- 1420-3049
New riminophenazines with pyrimidine and pyrazine substituents at the 2-position were successfully synthesized. The key step is the 2-N-arylation of riminophenazines with pyrimidine and pyrazine. The optimized reaction conditions involve the use of a Pd2(dba)3/DPPF/Cs2CO3/toluene combination.