This study investigated whether safe sex practices, including condom use and partner communication, may be predicted from the interpersonal traits of agency, unmitigated agency, communion, and unmitigated communion. Participants were 375 college students (77% women, 23% men), who completed an online questionnaire assessing the variables of interest. Hierarchical regression analyses revealed that high-agency individuals employed greater safe sex practices (p = .001) and had greater communication with their partners about safe sex (p