The prognostic value of microvascular invasion in early-intermediate stage hepatocelluar carcinoma: a propensity score matching analysis
- Resource Type
- article
- Authors
- Junyi Shen; Jun Wen; Chuan Li; Tianfu Wen; Lvnan Yan; Bo Li; Jiayin Yang; Changli Lu
- Source
- BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)
- Subject
- Microvascular invasion
Prognosis
Hepatocelluar carcinoma
Propensity score matching
Barcelona clinical liver Cancer
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
- Language
- English
- ISSN
- 1471-2407
Abstract Background Microvascular invasion (MVI) is well established as a negative prognostic factor for hepatocelluar carcinoma (HCC). However, its prognostic value in different subgroups of Barcelona Clinical Liver Cancer (BCLC) stages remains to be elucidated. Methods Four hundred fifty-eight MVI-negative and 204 MVI-positive patients who underwent hepatectomy were retrospectively analyzed. After propensity score matching (PSM) analysis, 187 pairs of matched patients were generated. Long-term survival was compared by the Kaplan–Meier method. Results Patients with MVI commonly had more advanced tumors. All the patients with MVI had significantly worse survival rate compared to the patients without MVI before and after PSM(p