Successful management of a colchicine overdose with plasmapheresis: a case report
- Resource Type
- article
- Authors
- İbrahim Halil Toksul; İbrahim Altundağ; Rıza Çete; Ziad Kazzi; Semih Korkut; Aynur Şahin
- Source
- Toxicology Communications, Vol 7, Iss 1 (2023)
- Subject
- Colchicine overdose
deliberate self-harm
plasmapheresis
lymphopenia
case report
Toxicology. Poisons
RA1190-1270
- Language
- English
- ISSN
- 24734306
2473-4306
19113641
AbstractAn overdose of colchicine can be lethal due to its narrow therapeutic index. We aimed to describe the successful management of a large intentional overdose with plasmapheresis therapy. A 32-year-old female presented to the Emergency Department with nausea, vomiting, and dizziness eight hours after intentionally ingesting 0.9 mg/kg colchicine in tablet form. She was treated with plasmapheresis and supportive therapy. The only abnormality in four days of observation was one-day transient lymphopenia (0.82 x 109/L).