目的::探讨中西医联合治疗和单纯西药治疗对心肌梗死介入治疗后二级预防患者的疗效。方法:将212例医院病例证实为急性心肌梗死介入治疗后患者,随机分为中西药结合组和西药组,其中西药组107例,中西药结合组105例,对所有入选患者3个月、6个月、12个月分别进行一次全面评估,包括体质指数、血压、血糖、血脂、肝功、肾功、心脏事件及患者住院次数,根据“2013年中华医学会冠心病康复与二级预防中国专家共识”实施药物干预,中西药组中的中药予以复方丹参滴丸3次/d,每次10粒。结果:中西药组在干预后3个月、6个月、12个月时,心脏事件及住院次数均比西药组下降,3个月时P <0.05,6个月、12个月时P <0.01,低密度脂蛋白在干预6个月( P <0.05)、12个月( P <0.01)两组比较差异有统计学意义;总胆固醇在干预12个月时中西药组与西药组比较有差异( P <0.05)。结论:心肌梗死介入治疗后患者二级预防,中西医联合治疗优于单纯西药治疗。
Objective:To explore the curative effect of combination of traditional Chinese and western medicine and single western medicine in secondary prevention on myocardial infarction after interventional therapy. Method:212 patients who received interventional therapy after acute my-ocardial infarction were randomly divided into the single western medicine group ( 107 cases ) and the traditional Chinese and western medicine combined group (105cases). An overall evaluation including body mass index, blood pressure, blood glucose, blood lipid, liver function, renal function, cardiac events and times hospitalization was made respectively 3 months, 6 months and 12 months later. According to"the consensus on rehabilitation of coronary heart disease and second prevention reached by experts of Chinese Medical Association in 2013 ", drug intervention was made in the two groups. 10 compound Danshen dripping pills were given to patients in the traditional Chinese and western medicine combined group each time for 3 times a day. Results:The occurrence rate of cardiac events and the times of hospitalization were decreased more significantly in the traditional Chinese and western medicine combined group than those in the single western medicine group after 3 months'intervention ( P <0. 05), 6 months' and 12 months' intervention ( P <0. 01); there was significant difference in the low density lipoprotein between the two groups after 6 months'intervention ( P <0. 05 )and 12 months'intervention ( P <0. 01) ;there was significant difference in the total cholesterol between the two groups after 12 months'intervention ( P <0. 05 ). Conclusion:Combination of traditional Chinese and western medicine is superior to single west-ern medicine in terms of secondary prevention for patients who received interventional therapy after acute myocardial infarction.