肥胖及中心性肥胖的发病率逐年增高,较明显的体征为脂肪累积、脂质含量增加,脂肪细胞肥大增生,进而产生一系列代谢异常,可致胰岛素抵抗.本文分析脂肪细胞参与胰岛素抵抗机制,从脾论治肥胖患者的病因病机,基于肥胖与脂肪组织的密切关系,阐释脾主运化与胰岛素抵抗联系.采用清热利湿法治疗肥胖型胰岛素抵抗患者疗效显著,可为减缓与逆转肥胖型胰岛素抵抗发展至糖尿病、改善临床症状提供帮助.
The incidence rate of obesity and central obesity is increasing year by year.The obvious signs are fat accumulation,increased lipid content,fat cell hypertrophy,and then a series of metabolic abnormalities,insulin resistance.By analyzing the involvement of adipocytes in the mechanism of insulin resistance and discussing the etiology and pathogenesis of obese patients from the perspective of spleen,based on the close relationship between obesity and adipose tissue,this article elucidated the relationship between spleen regulation and insulin resistance.It is effective to treat obese insulin resistance patients by clearing heat and removing dampness,which can help slow and reverse the development of obese insulin resistance to diabetes and improve clinical symptoms.