目的:了解颌骨成釉细胞瘤的构成现状,为临床诊疗提供帮助。方法:回顾性分析2003-01—2014-6间于我科住院治疗的890例颌骨成釉细胞瘤的临床资料,对其性别、年龄、发病部位、病理分类进行分析。结果:890例成釉细胞瘤中平均年龄40.15岁,男女比例1.62∶1。下颌骨受累724例(81.35%),上颌骨受累166例(18.65%),左右颌骨发病率基本相同,颌骨任一部位均可见成釉细胞瘤的发生,但下颌磨牙及下颌升支区为最易受累部位。病理亚型中实体型378例,单囊型427例,为成釉细胞瘤最为常见的病理亚型。结论:成釉细胞瘤好发于青年,多见于下颌骨,男性发病率较女性高,实体型及单囊型为成釉细胞瘤最为常见的病理亚型,临床诊治中应注意其相应特点。
Objective: To review the clinical and pathological manifestations of jaw ameloblastomas in order to provide reference for clinical diagnosis and treatment. Methods: Clinical data, pathological features, and therapeutic measures of 890 ameloblastomas were retrospectively analyzed. Results: Age of patients ranged between 6 to 101 years old, with an average of 40.15 years old. Gender distribution between males and females were about 61.91%(551/890) males to 38.08%(339/890) females, with a ratio of (1.62∶1). 724 cases (81.35%) occurred in the mandible, 166 cases (18.65%) occurred in the maxilla. The morbidity was equal on both sides of the jaws. Mandibular molar and ramus region was the most prevalent site for ameloblastoma. Solid(378/890) and unicystic ameloblastoma(427/890) were the most common pathological subtypes. Conclusion: Ameloblastoma mainly occurs in the mandible. A great part of the 890 cases are young individuals. Men are more vulnerable to this lesion than women. The different therapy and prognosis of ameloblastomas should be taken into ac-count in daily clinical works.