目的:探讨血清C反应蛋白(CRP)、甘油三酯(TG)等因素对急性胰腺炎(AP)病情严重程度的早期预测价值。方法:回顾性分析2014年3月至2016年3月我院收治的130例AP患者的临床资料。根据《急性胰腺炎国际共识———2012年亚特兰大修订版》,按患者病情严重程度,将病例分为轻症急性胰腺炎(MAP)组,中重症急性胰腺炎(MSAP)组和重症急性胰腺炎(SAP)组,比较三组病例的年龄、性别、胰腺炎病因、血淀粉酶、CRP、TG等指标。结果:单因素分析显示,MAP与MSAP+SAP组比较,CRP有显著性差异;MSAP与SAP组比较, CRP差异无统计学意义。针对高脂血症型急性胰腺炎(HLAP), MAP与MSAP+SAP组比较,TG无显著性差异。胰腺炎病因、性别、年龄、血淀粉酶水平与急性胰腺炎病情严重程度无明显相关性。结论:血清C反应蛋白可作为急性胰腺炎早期预后评估的指标之一,但尚不能作为判断MSAP和SAP的参考指标。血清TG≥11.3mmol/L是诊断高脂血症型急性胰腺炎的标准之一,但根据TG水平无法预测其病情发展及预后。
Objective: To explore the value of serum Creactive protein ( CRP) , triglyceride ( TG) and other factors in predicting the severity of acute pancreatitis ( AP) . Methods: 130 cases of AP patients from March 2014 to March 2016 in our hospital were retrospectively analyzed . According to "the acute pancreatitis international consensus - - 2012 Atlanta revised edition", and in the light of the severity of the disease, the patients were divided into mild acute pancreatitis ( MAP) group, moderately severe acute pancreatitis (MSAP) group and severe acute pancreatitis (SAP) group. The age, sex, cause of pancreatitis, serum amylase, CRP, TG and other indicators of the three groups were compared.Results: Single factor analysis showed that CRP in the MAP group was significantly different compared with the MSAP+SAP group; and CRP in MSAP and SAP groups had no significant difference. For hyperlipidemia acute pancreatitis ( HLAP) , TG in MSAP and SAP groups had no significant difference. There was no significant correlation between etiology, gender, age, serum amylase level and the severity of acute pancreatitis. Conclusion: Creactive protein can be used as a marker for the early prognosis of acute pancreatitis, but it can not be used as a reference index to judge the MSAP and SAP. Serum TG≥11.3mmol/L is one of the diagnostic criterias of hyperlipidemic acute pancreatitis, but the progression and prognosis of the disease cannot be predicted according to the level of TG.