The Beiya porphyry-skarn Au deposit is one of the largest gold deposits in China,temporally and spatially associated with Eocene intrusions in a post-collisional setting in western Yunnan,China.In this study,we report new whole-rock geochemistry,Sr-Nd isotope,zircon U-Pb geochronology and in situ zircon Hf-O isotopes of quartz-monzonite and biotite-monzonite porphyries from the Beiya deposit.The porphyry-skarn mineralization at the Beiya deposit is mainly associated with the quartz monzonite porphyry(35.8±0.6 Ma),while the biotite-monzonite porphyry(34.3±0.5 Ma)represents a post-mineralization intrusion crosscutting the main orebodies and the quartz-monzonite porphyry.Both intrusions have high-K and adakitic composition and are characterized by high Sr/Y ratios,high SiO2 and Al2O3 concentrations(SiO2=69.80-73.86 wt%;Al2O3=14.11-15.19 wt%),and low MgO,Cr,and Ni concentrations(MgO=0.2-1.0 wt%;Cr=1.76-11.13 ppm;Ni=2.52-11.72 ppm).Their Sr-Nd isotope compositions(87Sr/86Sr=0.7066-0.7077;eNd(t)=-5.3 to-1.5)are consistent with the lower crustal-derived amphibolite xenoliths(87Sr/86Sr=0.7060-0.7100;εNd(t)=-10.0 to 0.0),indicating that they might be derived from a thickened juvenile lower crust beneath the Yangtze Craton.The biotite-monzonite porphyry has lower zircon δ18O values of+5.3‰ to+6.8‰ and higher εH f(t)values of-2.3 to+5.5 than those of the quartz-monzonite porphyry with δ18O values of+7.1‰ to+8.2‰ and εHf(t)values of-3.8 to+1.5,implying that they were derived from different parts of the lower crust.High Ba/La and Pb/Ce ratios suggest that the quartz-monzonite porphyry is derived from a volatiles-rich reservoir.Relatively higher La/Yb,Sm/Yb and Dy/Yb ratios of the biotite-monzonite porphyry indicate residual garnet in the source,indicating a deeper source than that of the quartz-monzonite porphyry.The hydrous components should be represented by the amphibole-rich lithologies,which has relatively shallower depth than that of the garnet-bearing mafic thickened lower crust.Our data suggest that the mineralized quartz-monzonite porphyry at the Beiya deposit is derived from partial melting of amphibole-rich lithologies in the upper part of the thickened juvenile lower crust beneath the Yangtze Craton,while the post-mineralization biotite-monzonite porphyry is derived from the basal,and volatiles-poor,part of the juvenile lower crust.