目的:分析中医药治疗胰腺癌的研究现状、研究热点及发展趋势,为今后该领域的研究提供参考.方法:检索中国知网(CNKI)、维普(VIP)及万方(Wanfang)数据库中近20年相关文献,使用CiteSpace 6.1.R3软件对文献的作者、机构和关键词进行分析并绘制可视化图谱.结果:共纳入有效文献562篇,2003-2022年的发文趋势波动上升;本领域作者以刘鲁明、尤建良和张培彤为核心作者团队;研究机构合作图谱中复旦大学附属肿瘤医院为主要研究机构,也是跨机构、跨区域合作的代表机构;高频关键词有"验案""中医药""临床研究"等;共形成"胰腺癌""吉西他滨""情志护理""综述""数据挖掘"等12个关键词聚类.结论:中医药治疗胰腺癌的研究较多,研究热点集中在中医药治疗胰腺癌的机制探讨和疗效观察方面,其中伴随症状的治疗、生活质量、中医证型、用药规律成为近年来研究热点.未来研究者可从中医外治法的应用及疗效、中药汤剂的作用机制等方面进一步开展研究和探讨,以期开发中医药治疗胰腺癌的有效治疗手段.
Objective:To analyse the research status,research hotspots and development trends of traditional Chinese medicine(TCM)in the treatment of pancreatic cancer,and provide reference for future research and development in this field.Methods:Relevant literature from CNKI,VIP,and Wanfang databases over the past 20 years were retrieved,and the authors,organizations and keywords of relevant literature were analyzed and visual knowledge map was drew by CiteSpace software.Results:A total of 562 valid articles were included.The total number of published articles from 2003 to 2022 has increased year by year,and the article publication fluctuates on the rise.The core author teams in this field were LIU Luming,YOU Jianliang and ZHANG Peitong.In the research institution cooperation map,Fudan University Affiliated Cancer Hospital was the major research institution and also a representative institution for collaborating across agencies and regions.High frequency keywords including"medical case","TCM","clinical research",and etc.A total of 12 keyword clusters were formed,including"pancreatic cancer","gemcitabine","emotional nursing","review",and"data mining"and so on.Conclusion:There are many studies on the treatment of pancreatic cancer with TCM.The studies focus on the mechanism discussion and clinical efficacy of TCM in the treatment of pancreatic cancer.Among them,the treatment of accompanying symptoms,quality of life,TCM syndrome types,and medication rules have become research hotspots in recent years.In the future,researchers can conduct further research and discussion on the application and curative effect of external Chinese medicine treatment,and the mechanism of action of Chinese medicine decoction,in order to develop an effective treatment method for pancreatic cancer with TCM.