目的 探讨沙参麦冬汤辅治慢阻肺急性加重期的有效性.方法 随机选取2022年5月—2023年5月民乐县中医医院收治的70例慢阻肺急性加重期患者为研究对象,按照随机数表法分为两组,每组35例.对照组应用常规治疗方案,研究组在对照组基础上联合应用沙参麦冬汤治疗.对比两组的肺功能、血生化指标、症状缓解时间.结果 研究组第1秒用力呼气容积、用力肺活量、6 min步行距离均高于对照组,差异有统计学意义(P<0.05);治疗前,两组血生化指标比较,差异无统计学意义(P>0.05);治疗后,研究组C反应蛋白、中性粒细胞与淋巴细胞比值、嗜酸性粒细胞计数均低于对照组,差异有统计学意义(P<0.05);研究组症状缓解时间低于对照组,差异有统计学意义(P<0.05).结论 沙参麦冬汤辅治慢阻肺急性加重期的有效性值得肯定,有助于加快患者肺功能的改善速度,缩短其生化指标的恢复时间.同时,此种治疗形式利于缓解患者的各项临床症状,改善其预后.
Objective To explore the effectiveness of Shashen Maidong decoction in treating acute exacerbation of chronic obstructive pulmonary disease.Methods A total of 70 patients with acute exacerbation ofchronic obstructive pulmonary disease admitted to Minle County Hospital of Traditional Chinese Medicine from May 2022 to May 2023 were randomly selected as the research objects.According to the random number table method,they were divided into two groups,with 35 cases in each group.The control group was treated with conventional treatment,and the study group was treated with Shashen Maidong decoction on the basis of the control group.The lung function,blood bio-chemical indexes and symptom relief time were compared between the two groups.Results The forced expiratory vol-ume in the first second,forced vital capacity,and 6-minute walking distance in the study group were higher than those in the control group,and the differences were statistically significant(P<0.05).Before treatment,there were no statistically significant differences in blood biochemical indexes between the two groups(P>0.05).After treatment,the C-reactive protein,neutrophil to lymphocyte ratio and eosinophil count in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).The symptom relief time of the study group was lower than that of the control group,and the difference was statistically significant(P<0.05).Conclusion The ef-fectiveness of Shashen Maidong decoction in treating acute exacerbation of chronic obstructive pulmonary disease is worthy of affirmation,which helps to accelerate the improvement of patients'lung function and shorten the recovery time of their biochemical indexes.At the same time,this form of treatment can help to alleviate the clinical symptoms of patients and improve their prognosis.