过氧化物酶体增殖物激活受体γ(peroxisome proliferators-activated receptor-γ,PPAR-γ)是核受体超家族中的一员,具有调控脂质和糖代谢、抗炎、抑制自身免疫病等作用.PPAR-γ参与睑板腺发育和衰老过程,并通过抑制泪腺炎性因子产生、抑制结膜炎症、控制糖尿病和干燥综合征等全身病治疗干眼.
Peroxisome proliferators-activated receptor-γ( PPAR-γ) is a member of the nuclear re-ceptor superfamily .It has the ability of regulating lipid and glucose metabolization , anti-inflammatory and in-hibition of autoimmunity .PPAR-γmay be effective for treating dry eye through limiting the production of in-flammatory factors of the lacrimal gland , participating in development and aging of the meibomian gland , in-hibition of inflammation of the conjunctiva and controlling diabetes and Sj ?gren's syndrome.