目的 分析山东经不同性途径男性HIV感染者和艾滋病患者(HIV/AIDS)的流行病学特征.方法 通过我国"艾滋病综合防治信息系统"获取HIV/AIDS,纳入其中2007年1月1日至2016年12月31日期间自述感染途径为男男性行为传播或异性传播且现住址为山东的男性,共8584例.收集系统中研究对象的基本人口学特征、户籍和现住址,以及疾病进展、死亡等情况.比较不同性途径传播HIV研究对象的年龄差异、性行为构成差异.结果8584例研究对象中,经男男性行为传播者为6163例,被发现时年龄为(31.62±10.22)岁;经异性性行为传播者为2421例,被发现时年龄为(38.13±12.39)岁;年龄差异有统计学意义(t=24.95,P<0.001).2007—2008年经男男性行为传播者占38.7%(84例),经异性性行为传播者占62.2%(138例);2009—2016年经男男性行为传播者为6079例,经异性性行为传播者为2283例.研究对象中共770例死亡,其中经男男性行为传播感染HIV死亡者占43.8%(337例),经异性性行为传播感染HIV死亡者占56.2%(433例),差异有统计学意义(χ2=328.21,P<0.001).经男男性行为传播死亡者中,54.3%(183例)者从发现到死亡的存活时间不超过6个月,而经异性性行为传播者中该比例为61.4%(266例),差异有统计学意义(χ2=3.96,P=0.047).结论 男男性行为传播已成为山东省HIV的主要传播方式;经异性和同性性行为传播HIV的男性的流行特征有一定差异;部分病例从发现到死亡的存活时间较短.
Objective To analyze the epidemic features of male HIV-infected and AIDS patients by sexual transmission in Shandong Province. Methods Data on HIV-infected people and AIDS patients (HIV/AIDS) were derived from HIV/AIDS Comprehensive Response Information Management System. To analysis the epidemiological data of male HIV/AIDS by sexual transmission reported in Shandong Province from 1997 to 2016. Results A total of 8 584 HIV/AIDS were reported by heterosexual transmission or homosexual transmission from 2007 to 2016. 2 421 cases were reported by heterosexual transmission and 6 163 cases were reported by homosexual transmission.Among cases infected by heterosexual transmission. The average age of cases infected by heterosexual transmission was(38.13±12.39)and(31.62±10.22)among cases who infected by homosexual transmission(t=24.95,P<0.001).84 cases were reported by homosexual transmission and 138 cases by heterosexual transmission from 2007 to 2008,and 6 079 cases were reported by homosexual transmission and 2 283 cases by heterosexual transmission from 2009 to 2016.A total of 770 cases were dead after reported.Among the dead cases,337 cases were infected by homosexual transmission and 433 cases by heterosexual transmission(χ2=328.21,P<0.001).61.4% of the dead cases by heterosexual transmission were no longer than 6 months after reported and 54.3% in homosexual transmission(χ2=3.96, P=0.047). Conclusion Homosexual transmission has been the main transmission of HIV/AIDS in Shandong Province. Epidemiological features and social demographic characteristics of each sexual transmission were different.As part of HIV cases developed to death in 6 months.