We study the metallicity distribution and evolution in the Galactic disk based on the largest sample of open star clusters in the Galaxy. From the catalogue of 1879 open clusters in the range of Galactocentric distance (R_GC) from 4 to 20 kpc, we investigate the variation of metallicity in the Galactic disk as functions of R_GC, vertical distance (Z), and ages of the clusters. In the direction perpendicular to the Galactic plane, variation in metallicity is found to follow a stepped linear relation. We estimate a vertical metallicity gradient d[Fe/H]/dZ of -0.545+/-0.046 dex/kpc for |Z| < 0.487 kpc, and -0.075+/-0.093 dex/kpc for 0.487 < |Z| < 1.8 kpc. On average, metallicity variations above and below the Galactic plane are found to change at similar rates. The change in metallicity in the radial direction is also found to follow a two-function linear relation. We obtain a radial metallicity gradient d[Fe/H]/d[R_GC] of -0.070+/-0.002 dex/kpc for 4.0Comment: Accepted for publication in Frontiers in Astronomy and Space Sciences, 28 pages, 9 figures, 4 tables