The current proposal for the High Latitude Time Domain Survey (HLTDS) is two tiers (wide and deep) of multi-band imaging and prism spectroscopy with a cadence of five days (Rose et al., 2021). The five-day cadence is motivated by the desire to measure mid-redshift SNe where time dilation is modest as well as to better photometrically characterize the transients detected. This white paper does not provide a conclusion as to the best cadence for the HLTDS. Rather, it collects a set of considerations that should be used for a careful study of cadence by a future committee optimizing the Roman survey. This study should optimize the HLTDS for both SN Ia cosmology and other transient science.