In this paper, by mainly using the rearrangement technique and suitably constructing trial functions, under the constraint of fixed weighted volume, we can successfully obtain several isoperimetric inequalities for the first and the second Dirichlet eigenvalues, the first nonzero Neumann eigenvalue of the Witten-Laplacian on bounded domains in space forms. These spectral isoperimetric inequalities extend those classical ones (i.e. the Faber-Krahn inequality, the Hong-Krahn-Szeg\H{o} inequality and the Szeg\H{o}-Weinberger inequality) of the Laplacian.
Comment: 31 pages. Comments are welcome. Several typos have been corrected to v1