We present constraints on the amplitude of local Primordial Non-Gaussianities (PNG), $f_{\rm NL}$, using the quasar sample in the Sloan Digital Sky Survey IV extended Baryon Oscillation Spectroscopic Survey Data Release 16. We analyze the power spectrum monopole, testing for the presence of scale dependent galaxy bias induced by local PNG. Our analysis makes use of optimal redshift weights that maximize the response of the quasar sample to the possible presence of non zero PNG. We find $-4Comment: 26 pages, 10 figures, 3 tables. Comments are welcome