Association of high cardiovascular risk and diabetes with calcified carotid artery atheromas depicted on panoramic radiographs
- Resource Type
- Authors
- Eva Levring Jäghagen; Per Wester; Anna Norhammar; Jan Ahlqvist; Lars Rydén; Ulf Näslund; Nils Gustafsson
- Source
- Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 133:88-99
- Subject
- Carotid Artery Diseases
Male
medicine.medical_specialty
Carotid arteries
Radiography
Odontologi
Pathology and Forensic Medicine
Coronary artery disease
03 medical and health sciences
0302 clinical medicine
Risk Factors
Internal medicine
Diabetes mellitus
Radiography, Panoramic
Diabetes Mellitus
medicine
Humans
Radiology, Nuclear Medicine and imaging
Dentistry (miscellaneous)
Myocardial infarction
Periodontitis
Framingham Risk Score
business.industry
030206 dentistry
medicine.disease
Control subjects
Plaque, Atherosclerotic
Carotid Arteries
Cardiovascular Diseases
Heart Disease Risk Factors
Dentistry
030220 oncology & carcinogenesis
Cardiology
Female
Surgery
Oral Surgery
business
- Language
- ISSN
- 2212-4403
Objective: To evaluate whether estimates of risk of future cardiovascular events and death and established or unknown diabetes are significantly associated with calcified carotid artery atheromas (CCAAs) on panoramic radiographs (PRs). The main focus was on men and women without previous myocardial infarction (MI). Methods: The PAROKRANK (Periodontitis and its Relation to Coronary Artery Disease) study included patients with a first MI and matched control subjects. In this substudy, 738 patients (138 women) and 744 control subjects (144 women) with available PRs were assessed for CCAA. Cardiovascular risk estimates were determined according to the Framingham Risk Score (FRS) and Systematic COronary Risk Evaluation (SCORE). Established and previously unknown diabetes was also determined. Results: CCAA was detected on PRs in 206 control subjects (28%) and 251 patients (34%). FRS was significantly associated with CCAA among control subjects (P = .04) and patients (P = .001). SCORE was associated with CCAA among control subjects (P < .01) but not patients (P = .07). Among men, FRS and SCORE were associated with CCAA in both control subjects and patients. Diabetes was not significantly associated with CCAA after adjustments. Conclusions: Elevated cardiovascular risk scores were associated with CCAA on PRs among control subjects. Diabetes was not independently associated with CCAA, possibly owing to selection bias.